Digital Engineering for Inhalers: Robust Design Optimization of pMDI Valves

Name: Digital Engineering for Inhalers: Robust Design Optimisation of pMDI Valves
Start: 2026-04-09T15:00:00Z
End: 2026-04-09T16:00:00Z

Modelling and simulation (M&S) plays an increasingly critical role in Bespak R&D, supporting robust design optmisation, manufacturing efficiency, and the transition to more sustainable inhalation technologies. This webinar describes how advanced finite element analysis (FEA), meta-models of performance (MOP), and model-based systems engineering (MBSE) are applied across the pMDI product lifecycle, from design through manufacture. The results demonstrate how opportunities to relax tolerance limits can be identified without compromising device performance and quality, offering clear potential to reduce manufacturing waste.

The webinar concludes by outlining recent developments and future work, including viscoelastic material modelling, plans for in silico clinical trial methodologies, and the integration of M&S within a digital engineering workflow to support next-generation inhaler technologies and the transition to low-GWP propellants.

Date/Time:
April 9th, 2026
11:00 AM EDT / 3:00 PM GMT / 4:00 PM CEST

Venue:
Virtual

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Overview

Modelling and simulation (M&S) has become a vital component of Bespak’s R&D activities, enabling more effective design optimisation, improved manufacturing efficiency, and progress toward more sustainable inhalation solutions. This webinar explores the use of advanced finite element analysis (FEA), meta-models of performance (MOP), and model-based systems engineering (MBSE) throughout the pMDI product lifecycle, from initial design to manufacturing. The findings show how tolerance limits can be safely relaxed without negatively affecting device performance or quality, highlighting opportunities to reduce manufacturing waste. The session concludes with an overview of recent advances and future directions, including viscoelastic material modelling, the development of in silico clinical trial approaches, and the integration of M&S into a digital engineering framework to support next-generation inhalers and the shift toward low-GWP propellants.

What Attendees Will Learn

How advanced modelling and simulation methods—including FEA, MOP, and MBSE—are applied across the pMDI product lifecycle to support design optimisation and manufacturing efficiency.
How simulation-led insights can be used to relax tolerance limits without compromising device performance or quality, enabling reductions in manufacturing waste.
How digital engineering and emerging M&S capabilities—such as viscoelastic material modelling and in silico clinical trials—are shaping next-generation inhaler technologies and the transition to low-GWP propellants.

Who Should Attend

R&D engineers, simulation and modelling engineers, systems and MBSE engineers, product design and manufacturing engineers, quality and reliability engineers, engineering managers and technical leads, digital engineering specialists, sustainability leads, and pharmaceutical device development scientists.

Speakers

Karl Bass, PhD, Principal Model Based Systems Engineer, Bespak