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Accelerating Drug Development with Causal AI & Digital Twins: Ansys and Nova In Silico Partner for ISCT Solution

Bringing a new drug to market typically takes over a decade and costs between $1.5 to $2.6 billion, yet only about 5% of drug candidates entering clinical trials ultimately receive FDA approval. The high failure rate poses significant scientific and financial challenges. Causal AI has emerged as a promising solution, using mechanistic modeling and AI to inform human trials. To advance this capability, Ansys has partnered with Nova In Silico, a healthtech innovator based in Lyon, France. This collaboration will integrate Nova In Silico’s purpose-built Jinko trial simulation platform with Ansys Granta Data Management, delivering a unified solution to generate digital twins for In Silico Clinical Trials (ISCT). This integrated approach has the potential to significantly reduce R&D costs, accelerate timelines, and enhance clinical success rates across the biopharmaceutical industry.

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About this Event

Developing a new drug is a lengthy and costly process, often taking more than a decade and costing up to $2.6 billion; yet, fewer than 1 in 20 candidates entering clinical trials achieve FDA approval. To help address this challenge, the integration of causal AI and mechanistic modeling is offering a more predictive and efficient approach to drug development. Ansys has partnered with healthtech company Nova In Silico to advance this capability by combining Nova’s Jinko trial simulation platform with Ansys Granta Data Management. Together, they’re enabling the creation of digital twins for In Silico Clinical Trials (ISCT)—a powerful method for reducing R&D costs, accelerating development timelines, and improving the chances of clinical success in the biopharma sector.

What you will learn 

  • How in silico clinical trials and digital twins can help predict drug outcomes earlier in development, reducing the need for costly physical trials

  • The role of causal AI and mechanistic modeling in improving the accuracy and efficiency of trial simulations

  • How the integration of platforms like Jinko and Ansys Granta enables pharmaceutical companies to streamline R&D, lower risk, and boost clinical success rates

Speakers

François-Henri Boissel - Nova In Silico

Prasanth Bokam - Synopsys

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