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Improving the Biocompatibility of Medical Devices through Thrombosis Modeling

Blood-contacting medical devices such as heart pumps, valves, and oxygenators must not only restore circulation but also preserve the integrity of blood itself. Excessive shear stresses, turbulent flow patterns, and device-induced hemolysis remain significant challenges that compromise patient safety and clinical outcomes. Traditional testing methods to assess blood damage are costly, time-intensive, and limited in their ability to capture the full range of operating conditions a device will encounter. This creates a pressing need for predictive tools that can model complex blood–device interactions early in the design process.

Date/Time:
December 4th, 2025
11 AM EST / 5 PM CEST / 9:30 PM IST

Venue:
Virtual

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About this Event

In this session, we will explore how Ansys simulation technologies enable engineers to anticipate and mitigate blood damage through sophisticated physics-based modeling. By applying computational fluid dynamics alongside hemolysis prediction tools, teams can uncover areas of elevated shear stress, test alternative design configurations, and evaluate device performance across diverse clinical scenarios—all within a virtual environment. Practical examples will illustrate how this approach shortens development cycles, decreases reliance on animal studies and bench experiments, and supports the delivery of cardiovascular devices that are both safer and more effective for patients.

What you will learn 

  • How multiphysics simulation can predict blood damage in cardiovascular devices

  • Methods for combining computational fluid dynamics with hemolysis modeling to identify and address high-risk flow regions

  • Real-world examples showing how simulation reduces development time and minimizes reliance on animal and bench testing

  • Strategies for using simulation insights to optimize device design and improve patient safety outcomes

Speakers

  • Yang Yang, Ph.D. - Senior CAE Analyst, Cook Medical
  • Marc Horner, Ph.D. - Distinguished Engineer, Synopsys
  • Kurt Shivla - Lead Application Engineer, Synopsys
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