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A Solution to End-Stage Heart Failure: Total Artificial Hearts

End-stage heart failure remains one of the most pressing challenges in modern medicine, affecting millions worldwide and leaving many patients with limited treatment options. While heart transplantation is considered the gold standard, the persistent shortage of donor organs means that a significant number of patients never receive the life-saving therapy they need. Mechanical circulatory support devices such as ventricular assist devices (VADs) provide partial solutions, but they are not always sufficient for patients whose hearts have irreversibly lost function. In this context, Total Artificial Hearts (TAHs) emerge as a transformative alternative — fully replacing the native heart and restoring circulatory function.

Date/Time:
October 30, 2025
11:00 AM EST

Venue:
Virtual

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About this Event

Heart failure at its most advanced stage remains a critical global health issue, with many patients running out of effective treatment options. Although heart transplantation offers the best outcomes, the limited availability of donor hearts leaves countless individuals without a cure. Recent advances in biomedical engineering are paving the way for new possibilities. Among these innovations, Total Artificial Hearts stand out as a groundbreaking approach—designed to fully take over the heart’s function and sustain life when recovery is no longer possible. This event will delve into how these systems are being developed, tested, and refined to improve patient survival and quality of life, marking a bold step forward in the future of cardiac care.

What you will learn 

  • The clinical need for Total Artificial Hearts and how they address limitations of transplantation and ventricular assist devices.

  • Key engineering and design principles that enable safe and effective artificial heart function.

  • Current clinical outcomes, challenges, and future directions for TAH development.

  • The potential of Total Artificial Hearts to be used as a destination therapy in lower-income countries.

Speakers

  • Alabama Cawley, Team Lead, Team Bath Heart
  • Ben Green, Technical Lead, Team Bath Heart
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