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Virtuoso: A Virtual Platform for Precision Vascular Surgery

The clinical management of vascular disorders is challenging in terms of disease pathophysiology, risk factors and co-morbidities (among others) due to patient heterogeneity, all of which influence clinical decision making. To improve outcomes and patient satisfaction, the management of vascular diseases should be individualized. By exploiting advanced computational and 3D printing technologies we can generate more efficient, informative, and patient-specific workflows.

During this webinar, we will present a unique translational platform to enable precision vascular surgery (VIRTUOSO), combining state-of-the-art in vivo imaging, in silico (simulation) tools and in vitro testing in order to accurately quantify the hemodynamics of complex vascular pathologies, thereby informing individual treatment planning. To demonstrate the potential of this technology, which is entirely generalizable to other (cardio) vascular pathologies, we will use a complex and highly patient specific condition, chronic Type-B aortic dissection, as an example.

We will demonstrate how we use clinical data to build advanced patient-specific computational models of the pathology as well as 3D-printed phantoms for experimental testing and validation on a unique and personalizable flow circuit, thus overcoming major obstacles for clinical and industrial translation.

What you will learn:

  • Learn how to go from a patient-specific CT scan to hemodynamics results
  • Compare in vitro and in silico measurements and results
  • See how to guide clinical decision from simulation results



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