Leveraging Engineering Simulation in the Development of Vaccine Delivery Devices
Intranasal delivery can provide better protection than traditional injected vaccines for diseases such as influenza due to mucosal and cross-protection. But current intranasal delivery technology uses expensive and difficult-to-manufacture vaccines inefficiently. Creare has recently developed two novel vaccine delivery devices: a dry powder inhaler (DPI), which effectively delivers the vaccine dose to targeted regions of the nasal tract; and an ultra-compact InVaxTM intranasal nebulizer for liquid vaccines, which is an optimal platform for large-scale influenza vaccination.
Learn how Creare used Ansys Fluent for aerodynamic design and nasal deposition modeling in support of the DPI device development. Discover how analyses performed with Ansys Mechanical were used to design the piezoelectric actuator, a key component in the aerosol generation process for the InVax device.