healthcare conference

ANSYS Healthcare Innovation Conference

May 10, 2017

9:30 AM - 4:30 PM (EDT)


LabCentral, Inc.
700 North, Main Street
Cambridge, MA 02139

Liz Campbell

Regulatory, technological, and time-to-market demands are placing an ever-increasing value on the ability to verify and validate product and process performance in advance, before creating the first physical prototype.  ANSYS, setting the industry standard in CM&S (computer modeling & simulation), enables you to identify problems early in the design cycle when there is more flexibility to make changes.  This helps lower the time and cost of bringing new products to market, and significantly reduces failure and recall risk.

Join ANSYS at LabCentral in Cambridge, MA, a first-of-its-kind shared laboratory space designed as a launchpad for high-potential life-sciences and biotech startups, for a full day of presentations from customers and ANSYS technical experts on key topics affecting the healthcare industry, including:

  • Biogen
  • J&J DePuy
  • Amgen
  • Phenomyx
  • Granta Design

These presentations will illustrate how CM&S can provide additional evidence regarding product and process safety and efficacy, augmenting the safety and efficacy data gained from the classic approaches of bench testing, animal testing, and clinical trials.

We hope to see you at LabCentral on Wednesday, May 10th! Please register early to reserve your spot as space is limited and registration will be capped.

Parking Options

(0.2 miles) Technology Square, Garage - 800 Technology Square, Cambridge MA 02139 

(0.4 miles) One Kendall Square Garage - 389 Binney St., Cambridge, MA 02141

(0.4 miles) Ampco System Parking - 55 Franklin St., Cambridge, MA 02139

(0.4 miles) Cambridge Center West Garage - 77 Ames St., Cambridge, MA 02141


Time Topic
10:00 AM - 10:10 AM Welcome to LabCentral
10:10 AM - 10:30 AM ANSYS Welcome
Marc Horner, Ph.D., Technical Lead, Healthcare
10:30 AM - 11:15 AM Keynote: Biogen | Transforming Development & Manufacturing Paradigms using Predictive Models in Biopharmaceutical Operations
Suresh Nulu & Chris Johnson, Sr. Engineers, Engineering Technology 
11:15 AM - 12:00 PM Keynote: J&J DePuy | Computational Based Risk assessment of injury of Patients with Passive Spinal Implants During MRI Procedure 
Payman Afshari, Ph.D., Sr. Principal Engineer & Dan Moreno, Sr. Engineer
12:00 PM - 1:00 PM LUNCH
1:00 PM - 1:15 PM ANSYS Vision
Ubaldo Rodriguez, VP N. America Sales, ANSYS
1:15 PM - 1:45 PM Phenomyx | Phenotypic Screening of Cancer Cells
Salil Desai, Ph.D., CEO
1:45 PM - 2:15 PM Amgen | Product-Agnostic CFD Model for Single-Use Mixing System
Ahsan Munir, Ph.D., Senior Engineer
2:15 PM - 2:30 PM COFFEE BREAK
2:30 PM - 3:00 PM Granta Design Ltd. | Raising Your "Materials IQ"
John Twerdok, Director, Americas
3:00 PM - 3:30 PM Systems-level Analysis of an Insulin Pump
Marc Horner, Ph.D., Technical Lead, Healthcare


Biogen - Transforming Development & Manufacturing Paradigms using Predictive Models in Biopharmaceutical Operations
Suresh Nulu & Chris Johnson

In this talk, we provide a compelling overview of how predictive models are used at various stages of development and manufacturing in the biopharmaceutical industry. Case studies covering a wide range of the biologic product chain from drug substance to drug product and devices are presented to show how modeling contributes to the scientific advancement, strategic objectives, and bottom line of our technical operations at Biogen. While our main focus is on mainstream applications of CFD modeling in the biopharmaceutical industry, non-traditional uses of CFD and other first-principles modeling techniques will also be presented here. Through this presentation, we intend to provide inspiring perspectives on the value of predictive models and advocate their increased adoption in the biopharmaceutical industry.

J&J DePuy - Computational Based Risk assessment of injury of Patients with Passive Spinal Implants During MRI Procedure
Payman Afshari & Dan Moreno

The evidence generation paradigm using computational modeling and simulation (CM&S) for regulatory claims is evolving quite rapidly. Assessing the safety of patients implanted with passive devices scanned in an MR environment, through the use of CM&S, is one such example. In this instance, radio-frequency field interaction with the device could induce unsafe high temperatures in its surrounding tissues. The presentation will discuss the role of CM&S as a tool in generating evidence for MR device safety and cover topics such as worst-case selection methodology and computational model verification, validation and uncertainty quantification.

Phenomyx - Phenotypic Screening of Cancer Cells
Salil Desai

This presentation will cover the phenotypics of cancer. We will discuss the observations of cellular dynamics during cancer cell migration and the need for modeling complex biochemical networks to better understand such dynamic cellular behaviors. With a view to therapeutic development we will discuss our platform for massively parallel visualization and interrogation of cell-cell interactions. Such extensive studies of cellular interactions could provide invaluable insight in the development of cell-based therapeutics for cancer.  

Amgen - Product-Agnostic CFD Model for Single-use Mixing System
Ahsan Munir

In this presentation, we will cover how a product-agnostic multiphase computational fluid dynamics (CFD) model can be used to develop process design space for mixing in single use system. The simulated design space can be used to optimize impeller speeds in order to achieve the desired mixing for a given process conditions such as working volume and fluid properties. The presentation highlights the usage of CFD modeling in accelerating and designing single use system to formulate drug solutions. 

Granta Design - Raising Your “Materials IQ”
John Twerdok

Materials decisions in the Healthcare industry can be a matter of life or death. To make the best materials decisions, you need an intelligent strategy! This session provides a sound methodology for assessing your current “Materials IQ”. Learn how leading bio-med companies innovate with new materials to improve performance, reduce cost, lower risk, and ensure compliance with the latest regulatory statutes.

ANSYS - Systems-level Analysis of an Insulin Pump
Marc Horner

This presentation will review a multi-domain model of an insulin pump as an example of how the ANSYS digital system prototyping platform enables engineers from diverse backgrounds to work in unison to achieve a deep understanding of integrated product behavior. It will include an overview of how ANSYS tools can be used to analyze various pump components, followed by a live demo of a Simplorer model of the drug delivery sub-system. The Simplorer model incorporates many of the key elements of this sub-system, including a display, controller, power electronics, hydraulics, and a ROM, all working together as a system.